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differential management rheumatology treatment tuberculosis workup activetb infections latenttb syndrome ana antinuclear erythematosus hepatology neurology opportunistic systemic testing abnormal activation
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
characteristic features Clinical ... Tuberculosis Diagnosis ... staining, NAA (PCR ... HIV-infected patients should ... #Diagnosis #Management
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
characteristic features Clinical ... Tuberculosis Diagnosis ... staining, NAA (PCR ... HIV-infected patients should ... #Diagnosis #Management
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
healthy adults, and should ... likely it will be clinically ... , Drug-induced Lupus ... ANA #patterns #rheumatology ... #diagnosis #differential
Abnormal liver function tests algorithm. This figure details the initial response to abnormal liver blood tests.
Areas of diagnostic ... alcohol-related liver disease ... non-alcoholic fatty liver disease ... Abnormal #Algorithm #Hepatology ... #Differential #Diagnosis
Tuberculosis Testing LATENT TB • LTBI is diagnosed when an asymptomatic patient has a positive TST or IGRA
Testing LATENT TB ... • LTBI is diagnosed ... result with no clinical ... intermediate risk of disease ... LatentTB #ActiveTB #InfectiousDiseases
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Differential Diagnosis ... Malignancy (e.g. hematologic ... La, anti-Jo-1, SCL ... Erythematosus #Diagnosis
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
Association with disease ... -15% If SLE is clinically ... suspected, tests ... erythematosus #diagnosis ... #rheumatology #
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
joint • Systemic lupus ... should be obtained ... (to support a diagnosis ... ANA and RF (if clinical ... laboratory #workup #diagnosis
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
Viral Infection Clinical ... Hemoglobinuria (PCH ... Test: Donath-Landsteiner ... test #cold # ... hemolytic #anemia #hematology
Macrophage Activation Syndrome (MAS) Classified among the secondary or acquired forms of haemophagocytic lymphohistiocytosis (sHLH) What? A subset of
• Systemic lupus ... SJIA], systemic lupus ... Liver function tests ... Activation #Syndrome #Diagnosis ... #Management #Hematology
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