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management rheumatology treatment tuberculosis latenttb lupus erythematosus sle table testing active ana antinuclear arthritis aspergillus autoantibodies betadglucan biomarkers chronic cll
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
characteristic features Clinical ... Active TB: • ... staining, NAA (PCR ... HIV-infected patients should ... #Diagnosis #Management
Tuberculosis Overview 10 million new M. tuberculosis infections/year Facultative intracellular rod-shaped bacteria Multidrug-resistant tuberculosis (MDR-TB) accounts for 4.6% of
characteristic features Clinical ... Active TB: • ... staining, NAA (PCR ... HIV-infected patients should ... #Diagnosis #Management
Tuberculosis Testing LATENT TB • LTBI is diagnosed when an asymptomatic patient has a positive TST or IGRA
Testing LATENT TB ... • LTBI is diagnosed ... result with no clinical ... intermediate risk of disease ... #Workup #TB #Latent
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... affected joint • Systemic ... should be obtained ... ANA and RF (if clinical ... #diagnosis #testing
IgG4-Related Disease Clinical history: Man, 60 years, multiorgan involvement, unique or multiple inflammatory pseudotumor 4 phenotypes: •
IgG4-Related Disease ... Clinical history ... female, asian • Systemic ... specific laboratory tests ... #phenotypes #workup
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
SLE (Systemic Lupus ... ) Suspect: Clinical ... Differential Diagnosis ... La, anti-Jo-1, SCL ... Erythematosus #Diagnosis
Antinuclear antibodies and Systemic lupus Anti-dsDNA 60-80% Association with disease activity (when with Farr assay) and lupus nephritis. Can
antibodies and Systemic ... activity (when ... -15% If SLE is clinically ... suspected, tests ... erythematosus #diagnosis
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
adults in the west ... Orange or Hep C Clinical ... cells can indicate disease ... #workup #oncology ... #hematology
Drug Induced Lupus vs SLE Drug Induced Lupus (DIL): • Epidemiology: -10% of all lupus cases, drug-dependent,
to 1:1 F:M • Clinical ... months to years) Systemic ... Evolution: Chronic disease ... druginduced #lupus #sle #comparison ... #diagnosis #management
IDSA Recommendations for Treating Mycobacterium Tuberculosis Infection and Disease in HIV-AIDS Treating LTBI (to prevent TB disease) Indications:
Infection and Disease ... TB Disease: • ... and molecular diagnostic ... treatment should ... HIV-infected persons with clinical
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