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differential management erythematosus lupus symptoms systemic autoantibodies dermatology msk pain rheumatoid sle syndrome workup ana antinuclear cppd dermatomyositis gout pseudogout
Synovial Fluid Analysis: Findings (COLOR TRANSPARENCY VISCOSITY WBC COUNT (PER MM3) PMN CELL COUNT (%) GRAM STAIN CULTURE PCR TEST CRYSTALS) By Condition (Normal Noninflammatory Inflammatory:
TEST CRYSTALS) ... nongonococcal ) #Diagnosis ... Arthrocentesis #Joint ... Effusion #Analysis #Table ... Septic #Infective #Arthritis
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 Rheumatoid Arthritis Summary Overview: chronic, inflammatory symmetric polyarthritis involving small joints of hands/feet, knees, shoulders Signs & Symptoms:
Rheumatoid Arthritis ... hands/feet, knees, shoulders ... Signs & Symptoms ... #Rheumatoid #Arthritis ... #rheumatology
Approach to Joint Pain History: Is the pain from: • Joint • Adjacent bursa • Tendon • Ligament • Bone • Muscle • Referred from
Disease: • Pain ... disease must be ... present both at rest ... #Pain #MSK #rheumatology ... #differential #diagnosis
Rheumatology Workup - Laboratories Studies in Rheumatic Diseases • Septic arthritis - Gram stain and culture of
Rheumatology Workup ... double-stranded DNA antibodies ... should be obtained ... (to support a diagnosis ... #testing #Rheumatology
Autoantibodies and their Disease Associations ANA - Non-specific; common in SLE, autoimmune hepatitis Anti-CCP, Rheumatoid factor - RA Anti-dsDNA
Autoantibodies and their Disease ... syndrome Anti-Scl ... #diagnosis #table ... #rheumatology # ... antibodies
Approach to Joint Pain - Arthritis Differential Diagnosis Framework Inflammatory Versus Noninflammatory Pain • Is it inflammatory
Differential Diagnosis ... axial (spine, shoulders ... noninflammatory Signs ... #Diagnosis #MSK ... #rheumatology #
Causes of Bone/Joint Pain in Sickle Cell Disease Vaso-occlusive pain: • Mechanism: ischemic pain • Can present
Causes of Bone/Joint ... common sites: hip, shoulder ... Osteomyelitis / Septic Arthritis ... #differential #diagnosis ... #causes #hematology
Antinuclear Antibodies (ANA) ANA or Anti-NucIear Antibody refers to antibodies against antigens in the nucleus → like
Antinuclear Antibodies ... Antibody refers to antibodies ... healthy adults, and should ... ANA #patterns #rheumatology ... #diagnosis #differential
Gout (Gouty Arthritis) - MSK Radiology Imaging Findings: • Eccentric soft-tissue densities surrounding the third proximal interphalangeal
Gout (Gouty Arthritis ... mass and NO prior signs ... • This case should ... diffuse chondral disease ... #msk #rheumatology
Behçet's Syndrome Systemic disease associated with inflammation of multiple organs, small-vessel vasculitis and large-vessel vasculopathy Epidemiology: • Young
Positive pathergy test ... is a skin prick test ... ) Differential Diagnosis ... #management #signs ... #symptoms #rheumatology
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