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Acid-Base Disorders - Differential Diagnosis Algorithm Acidemia (pH < 7.35) • Metabolic Acidosis (HCO3 < 24mmol/L) CO2
Acid-Base Disorders ... HCO3 < 24mmol/L) CO2 ... Respiratory Acidosis (pCO2 ... HCO3 > 28mmol/L) CO2 ... Respiratory Alkalosis (pCO2
Acid Base Compensation - Directions - If all three variables (pH, HCO2, pCO2) move in the
Acid Base Compensation ... variables (pH, HCO2 ... , pCO2) move in
PLACO Mnemonic - Approach to Acid-Base Disorders P - Determine the pH L - Labs: PCO2 & HCO3 A
- Approach to Acid-Base ... pH L - Labs: PCO2 ... PLACO #AcidBase #Acid
Acid Base and Blood Gas Analysis 1. pH - What’s the primary disturbance? 2. pCO2 - What’s the
Acid Base and Blood ... 2. pCO2 - What’s ... the pCO2? ... Medications, Central, ↑ CO2
Oxygen-Hemoglobin Dissociation Curve Left Shift (↓ O2 unloading to tissue), Left = Lower: • ↓ H+ (↑
+ (↑ pH) • ↓ PCO2 ... tissue): • ↑ H+ (Acid ... ) • ↑ PCO2 •
Acid Base Disorders Worksheet Step 1: Gather the necessary data (Na+, CI-, HCO3-, PH, pCO2). Preferably, all
Acid Base Disorders ... CI-, HCO3-, PH, pCO2 ... 3: Look at the pCO2 ... . 3a: If pCO2 ... joshsteinbergMD #Acid
Blood Gas (ABG) Interpretation and Acid-Base Pathology 1- Does the patient have an acidosis or an alkalosis?
Interpretation and Acid-Base ... Look at the pCO2 ... Metabolic Equal (If pCO2 ... the change in pCO2 ... Amy Chung, MD, MSc
Basics of Waveform Capnography Waveform capnography assesses ventilation by monitoring exhaled carbon dioxide Can use measurement and morphology
pathophysiology CLINICAL ... Assessing for CO2 ... Transition as CO2 ... - Arterial CO2 ... WAVEFORM - Critical
#ICUCard RENAL GFR 90-131 mL/min ((140-age)*Wt)/(72*Cr) Glomerular Filtration Rate (Cockcroft) CI Cr 90-131 mL/min (CrU * volume)/CrS Creatinine Clearance FENa 0.0-1.0 % ((U/P Na)/(U/P Cr))*100 Fractional Excretion of Na+ Na req mEq (125-Na)*0.6*Wt Required Sodium FE Urea
Osmolar Gap ACID-BASE ... H_def 0 mEq Acid ... pCO2 = 1.5 (HCO3 ... )/HCO3 Acid base ... 70 mmHg on 100% mask
Acid Base Disorders - Blood Gas Interpretation Steps for Blood Gas Interpretation: 1. Acidemia or Alkalemia? 2.
Acid Base Disorders ... 7.35-7.45 • PaCO2 ... 35-45 mmHg • PaO2 ... Metabolic: pH pCO2 ... ABG #bloodgas #Acid
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