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Acid-Base Disorders - Differential Diagnosis Algorithm
Acidemia (pH < 7.35)
• Metabolic Acidosis (HCO3 < 24mmol/L) CO2

pH < 7.35) • Metabolic ... Acidosis (HCO3 ... • Respiratory Acidosis ... pH > 7.45) • Metabolic ... #Causes #Compensation

Acid Base and Blood Gas Analysis
1. pH - What’s the primary disturbance?
2. pCO2 - What’s the

2. pCO2 - What’s ... the pCO2? ... Medications, Central, ↑ CO2 ... gap metabolic acidosis ... acidbase #workup #algorithm

Arterial Blood Gas (ABG) Analysis - Metabolic + Respiratory Acidosis + Alkalosis

pH ↓ pCO2 ↓ -

ABG) Analysis - Metabolic ... ↓ - Metabolic acidosis ... pH ↑ pCO2 ↑ - ... Metabolic alkalosis ... pH ↑ pCO2 ↓ -

Acid Base Disorders - Blood Gas Interpretation

Steps for Blood Gas Interpretation:
1. Acidemia or Alkalemia?
2.

Acute or chronic ... : pH pCO2 ↓ ... ↓ Metabolic Acidosis ... Compensation, Acute ... Metabolic acidosis

Acid Base Compensation - Directions - If all three variables (pH, HCO2, pCO2) move in the

variables (pH, HCO2 ... , pCO2) move in ... Nephro #AcidBase #Acidosis ... #Alkalosis #Metabolic

Blood Gas (ABG) Interpretation and Acid-Base Pathology
1- Does the patient have an acidosis or an alkalosis?

patient have an acidosis ... Look at the pCO2 ... Equal (If pCO2 ... the change in pCO2 ... acidosis, you need

Approach to Acid Base Disorders - Evaluation and Differential Diagnosis
1) Start with the Anion Gap (AG).
2)

and ~5 mmHg to pCO2 ... the chronicity (acute ... , chronic, or acute ... • Anion Gap Metabolic ... Non-Anion Gap Metabolic

Acid-Base Disorders - Expected Compensation Equations

Metabolic Acidosis:
• pCO2 = 1.5 x HCO3 + 8 ±

Acidosis: • pCO2 ... ↓ 1.2 Metabolic ... Respiratory Acidosis ... : • Acute: ∆ pCO2 ... Alkalosis: • Acute

Acid Base Disorders Worksheet

Step 1: Gather the necessary data (Na+, CI-, HCO3-, PH, pCO2). Preferably, all

has a primary acidosis ... patient's alkalosis is metabolic ... >40 patient's acidosis ... <40 patient's acidosis ... is metabolic Step

Blood Gas Analysis and Interpretation
STEPS TO ANALYSIS
1. Look at PH. Alkalotic or acidotic?

Alkalotic or acidotic ... - If acidotic ... - pCO2 (respiratory ... Bicarb/BE/BD (metabolic ... respiratory or metabolic

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