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Guillain-Barre Syndrome - Summary

Acute AIDP that presents with rapidly progressive flaccid weakness

Epidemiology:
 • 1-2 cases/100,000 per
Guillain-Barre Syndrome ... cases/100,000 per ... response preceding infection ... Diagnosis: • ... #treatment #neurology
Pulmonary Renal Syndrome

Definition: Diffuse alveolar hemorrhage + Glomerulonephritis
Presentation (Pulmonary and renal manifestations can occur weeks apart):
Differential Diagnosis ... allopurinol), Infection ... • Labs: CBC, cr ... Bronchoscopy with serial ... #nephrology
Some of the techniques used for Antenatal Diagnosis

Amniocentesis 
 - Chromosome/micro-array and DNA analysis 
 -
PCR Fetal blood ... serology - Fetal ... — PCR - Enzyme ... invasive surgery, e.g ... transfusion syndrome
Blood Culture-Negative Infective Endocarditis (BCNIE)
Definition: No etiology found after 3 separate blood cultures remain negative for
requires special media ... BCNIE Diagnostic ... antiphospholipid syndrome ... - PCR for ... differential #workup #infectiousdiseases
CNS Infection in HIV / AIDS - Differential Diagnosis Framework

Principles of HIV-Associated CNS Opportunistic Infections:
 •
- Differential Diagnosis ... μL • Diagnosis ... headache, altered mental ... opportunistic #InfectiousDiseases ... #Neurology
Guillain-Barré Syndrome (GBS)
Acute autoimmune demyelinating polyradiculoneuropathy that presents with rapidly progressive flaccid weakness
Epidemiology:
 • Incidence: 1
Guillain-Barré Syndrome ... Electrodiagnostic studies (Ex EMG ... SinaiBmoreIMRes #GBS #Guillain ... #Barre #Syndrome ... #neurology
Approach to Headaches - Differential Diagnosis Algorithm

Red flags (PHANTOMS):
 • Pattern change, progressively worse, papilledema
 •
- Differential Diagnosis ... papilledema • Horner syndrome ... lyme • Altered mental ... lesion • CNS infection ... #Algorithm #neurology
Causes of Fatigue - Differential Diagnosis Algorithm
Endocrine
 • Hypo/Hyperthyroidism
 • Diabetes
 • Pituitary Insufficiency
 • Adrenal
• Malignancy Infectious ... Chronic Obstructive Pulmonary ... Disease Neurologic ... • Drug Abuse (e.g ... Chronic Fatigue Syndrome
Weakness - Differential Diagnosis Framework

Approach To Weakness:
 • Non-neuromuscular disorder (Cardiac, pulmonary etc)
 • CNS ->
- Differential Diagnosis ... disorder (Cardiac, pulmonary ... electromyographic (EMG ... #Differential #Diagnosis ... #neurology
Cauda Equina Syndrome Overview

Cauda Equina Syndrome:
 • Prevalence: 1:33,000-100,000 ppl/yr
 • Incidence: 1.5-3.4 million ppl/yr
 •
Differential Diagnosis ... toon • Spinal infection ... Tethered cord • Guillain-Barre ... #differential #diagnosis ... #causes #neurology