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auerrods clinical diagnosis hematology blood bloodsmear oncology acutepromyelocyticleukemia leukemia mds myelodysplasia myelodysplastic nejm pancytopenia syndromes workup
A 37-year-old woman initially presented with pancytopenia and found to have leukopenia (2.1 × 103/μL) with
promyelocytic leukemia (APL ... treatment, her peripheral ... , Auer rods in neutrophils ... #Clinical #Path ... #Microscopy #Auer
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 Auer Rods - Bone marrow aspiration revealed 5% blasts and 65% promyelocytes; many promyelocytes had prominent
Auer Rods - Bone ... rods (arrows) and ... #Clinical #Path ... #APL #AuerRods # ... #Smear #Microscopy
Here are very large, immature myeloblasts with many nucleoli. A distincitve feature of these blasts is
myelogenous leukemia (AML ... #Clinical #Path ... BloodSmear #Blood #Smear ... #Microscopy #Auer ... #AML
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
blood smear or ... -> AML: Blast crises ... Age: 50-60 • Auer ... Rods Significant ... smear: Blasts
Pancytopenia - Differential Diagnosis Algorithm • 12-13 g/dL, • ANC < 1800/uL, • platelet < 150,000/uL Initial
Diagnosis Algorithm ... 12-13 g/dL, • ANC ... BMP, uric acid, peripheral ... smear, reticulocyte ... Matthew Ho, MD PhD
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Smear: • Dysplastic ... involve one, two, or all ... transformation to AML ... blood count with differential ... progression to AML
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