12 results
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
I see all of these ... promyelocytic #leukemia #APL ... #APML #Pathology ... #Hematology #Clinical
Classic mucosal-dominant Pemphigus Vulgaris. Suprabasal acantholysis leaving behind a “row of tombstones” (i.e. the basal layer
mucosal-dominant Pemphigus ... mucosal #dominant #Pemphigus ... #Vulgaris #Pathology ... #Microscopy #Dermatology ... #Clinical
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
#neutrophils #AML ... #Clinical #Hematology ... #Pathology #Smear
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... Incidence: common in APL ... Infection (sepsis), PE ... Differentiation #Syndrome #APML ... diagnosis #management #hematology
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
Myeloid Leukemia (AML ... Smear #Peripheral #Pathology ... #Microscopy #Clinical
Pretty good example of Pemphigus Vulgaris. DIF shows intercellular IgG binding throughout entire epidermis. Note there’s
good example of Pemphigus ... SGottesmanMD #Pemphigus ... #Vulgaris #Pathology ... #Microscopy #Dermatology ... #Clinical
Leukemic skin Infiltrate: Patient with known Acute Myelogenous Leukemia presented with diffuse
bullous lesions (not shown). These
UCSD Catalog of Clinical ... Images #Clinical ... #Photo #Dermatology ... Leukemic #Infiltrate #AML
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
10d, venous (DVT/PE ... Diagnosis: • Clinical ... Management: • D/c all ... non-heparin A/C if clinical ... Management #Treatment #Hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
involve one, two, or all ... transformation to AML ... abnormal under a microscope ... progression to AML ... Syndromes #diagnosis #hematology
Essential Thrombocythemia (ET)
ET is a chronic myeloproliferative neoplasm. Most cases are related to mutations that affect
MI, stroke, DVT/PE ... generally requires all ... transformation into MDS or AML ... Thrombocythemia #ET #hematology ... diagnosis #management #hematology