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hematology diagnosis smear leukemia microscopy oncology aml management algorithm apl auer blood cancer causes chronic cll damage differentiation disease exposure
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
Acute promyelocytic ... #Auer #Rods #Acute ... promyelocytic #leukemia #APL ... #APML #Pathology ... #Hematology #Clinical
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... Release from blast cells ... • Induce blast cell ... Infection (sepsis), PE
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... (Acute Myeloid ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology
Hypersegmented neutrophil in a case of acute myeloid leukemia. Dysplastic neutrophils are typically hypolobated but can be
neutrophil in a case of acute ... #neutrophils #AML ... #Clinical #Hematology ... #Pathology #Smear
Prolymphocytes In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML). 🔬Tumor
leukemia (T-PLL) not Acute ... Myeloid Leukemia (AML ... 🔬Tumor cells are ... Smear #Peripheral #Pathology ... #Microscopy #Clinical
A non-subtle example of true Sezary syndrome. Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... #Pathology #Smear ... #Microscopy #Hematology
Acute Graft versus Host disease: vacuolar interface dermatitis w/ lymphoexocytosis, dyskeratotic keratinocytes, notable satellite cell necrosis.
Acute Graft versus ... notable satellite cell ... Host #disease #Pathology ... #Microscopy #Dermatology ... #Clinical
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... • Richter’s Syndrome ... Transform to DLBCL, PML ... ’s lymphoma or acute ... leukemia • Sezary syndrome
Leukemic skin Infiltrate: Patient with known Acute Myelogenous Leukemia presented with diffuse bullous lesions (not shown). These
Patient with known Acute ... of leukemic cells ... Images #Clinical ... #Photo #Dermatology ... Leukemic #Infiltrate #AML
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... presents as an acute ... Low or absent NK cell ... management #treatment #hematology
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