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hematology diagnosis oncology leukemia algorithm cancer cll differentiation lymphocytic management mds myelodysplasia myelodysplastic syndromes workup
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... -> AML: Blast crises ... develop leukostasis syndrome ... smear: Blasts APML ... • Tumor lysis syndrome
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... Incidence: common in APL ... Infection (sepsis), PE ... #APML #diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
involve one, two, or all ... transformation to AML ... Marrow Failure • Chronic ... progression to AML ... #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... • Richter’s Syndrome ... Transform to DLBCL, PML ... leukemia #CLL #Chronic
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
Myelodysplastic syndromes ... myeloid leukemia (AML ... cytopenias and AML ... with repeated red cell ... importance of clinical
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