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hematology diagnosis oncology leukemia management smear acute algorithm apl auer blood cancer chronic differentiation hemophagocytic hlh lymphocytic lymphohistiocytosis mds microscopy
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, CML, AML, APML ... Lymphadenopathy AML ... cutaneous plaques) AML ... smear: Blasts APML ... • Tumor lysis syndrome
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
I see all of these ... promyelocytic #leukemia #APL ... #APML #Pathology ... #Hematology #Clinical
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... • Richter’s Syndrome ... Transform to DLBCL, PML ... leukemia • Sezary syndrome ... workup #oncology #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
in APML Epidemiology ... Incidence: common in APL ... • Induce blast cell ... Infection (sepsis), PE ... #APML #diagnosis
Prolymphocytes In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML). 🔬Tumor
T-prolymphocytic leukemia (T-PLL ... Myeloid Leukemia (AML ... 🔬Tumor cells are ... Smear #Peripheral #Pathology ... #Microscopy #Clinical
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
involve one, two, or all ... transformation to AML ... Myelogenous Leukemia (CML ... progression to AML ... #diagnosis #hematology
Hemophagocytic Lymphohistiocytosis (HLH) Definition: Overwhelming clinical syndrome associated with excessive macrophage activation and cytokine storm due to
: Overwhelming clinical ... syndrome associated ... Low or absent NK cell ... Ferritin >500 ng/mL ... management #treatment #hematology
Myelodysplastic syndromes current treatment algorithm 2018. From Blood Cancer Journal, Published 24 May 2018 Myelodysplastic syndromes (MDS) are
Myelodysplastic syndromes ... myeloid leukemia (AML ... cytopenias and AML ... with repeated red cell ... importance of clinical
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