18 results
diagnosis hematology management oncology leukemia microscopy rheumatology smear acanthocytes agglutinin algorithm anemia atrophy cancer causes chronic cll cold common cryofibrinogenemia
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... Release from blast cells ... • Induce blast cell ... Infection (sepsis), PE
A non-subtle example of true Sezary syndrome. Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... #Pathology #Smear ... #Microscopy #Hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
, APML, CLL Acute ... extramedullary disease ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology
Acute Graft versus Host disease: vacuolar interface dermatitis w/ lymphoexocytosis, dyskeratotic keratinocytes, notable satellite cell necrosis.
Graft versus Host disease ... notable satellite cell ... #versus #Host #disease ... #Pathology #Microscopy ... #Dermatology #Clinical
Beautiful acanthocytes/spur cells in a patient with McLeod Syndrome. X-linked disorder characterized by reduced expression of
acanthocytes/spur cells ... patient with McLeod Syndrome ... granulomatous disease ... #Smear #Pathology ... #Microscopy #Clinical
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Plasma cell leukemia ... Aggressive disease ... rouleaux #formation #Clinical ... #Smear #Hematology ... #Pathology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Myelodysplastic Syndromes ... transformation to AML ... Myeloproliferative Disease ... progression to AML ... #diagnosis #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... can indicate disease ... • Richter’s Syndrome ... Transform to DLBCL, PML ... leukemia • Sezary syndrome
Dermatologic Manifestations of Granulomatosis with Polyangiitis (GPA) Skin involvement in granulomatosis with polyangiitis (GPA) is common and
Dermatologic Manifestations ... Rarely dominate the clinical ... • Goodpasture syndrome ... • Giant cell arteritis ... vasculitis #Dermatologic
Sjogren's Syndrome Overview Epidemiology: • F > M: 9:1 • 5-6th Decades (can be any age) Autoimmune exocrinopathy multisystemic disease
Sjogren's Syndrome ... SLE • Mikulicz syndrome ... ducts Clinical ... effusion, INC risk PE ... #Sjogrens #Syndrome
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