12 results
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia ... promyelocytic #leukemia ... #APL #APML #Pathology ... #Hematology #Clinical
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
APML, CLL Acute ... develop leukostasis syndrome ... smear: Blasts APML ... • Tumor lysis syndrome ... #Hematology #Oncology
Prolymphocytes

In our case, the patient has T-prolymphocytic leukemia (T-PLL) not Acute Myeloid Leukemia (AML).  🔬Tumor
T-prolymphocytic leukemia ... (AML). ... 🔬Tumor cells are ... Smear #Peripheral #Pathology ... #Microscopy #Clinical
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
acute myeloid leukemia ... #neutrophils #AML ... #Clinical #Hematology ... #Pathology #Smear
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... • Richter’s Syndrome ... Transform to DLBCL, PML ... syndrome • Smoldering ... adult T cell leukemia
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Plasma cell leukemia ... primary plasma cell ... rouleaux #formation #Clinical ... #Smear #Hematology ... #Pathology
Leukemic skin Infiltrate: Patient with known Acute Myelogenous Leukemia presented with diffuse
bullous lesions (not shown). These
cells. ... UCSD Catalog of Clinical ... Images #Clinical ... #Photo #Dermatology ... #Infiltrate #AML
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... in APML Epidemiology ... Release from blast cells ... • Induce blast cell ... Infection (sepsis), PE
A non-subtle example of true Sezary syndrome.  Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... #Pathology #Smear ... #Microscopy #Hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
transformation to AML ... Chronic Myelogenous Leukemia ... • Hairy Cell Leukemia ... progression to AML ... #diagnosis #hematology