17 results
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic #leukemia #APL ... #APML #Pathology ... #Hematology #Clinical
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
#neutrophils #AML ... #Clinical #Hematology ... #Pathology #Smear
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome ... Infection (sepsis), PE ... Differentiation #Syndrome ... #APML #diagnosis ... #management #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Chronic leukemia ... with a relatively chronic ... develop leukostasis syndrome ... • Tumor lysis syndrome ... #Leukemia #Hematology
A non-subtle example of true Sezary syndrome.  Patient presented with erythroderma without antecedent history of
of true Sezary syndrome ... mjcascio #Sezary #Syndrome ... #Cells #Clinical ... #Pathology #Smear ... #Microscopy #Hematology
Beautiful acanthocytes/spur cells in a patient with McLeod Syndrome. X-linked disorder characterized by reduced expression of
patient with McLeod Syndrome ... associated with chronic ... SpurCells #McLeod #Syndrome ... #Smear #Pathology ... #Microscopy #Clinical
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... • Richter’s Syndrome ... Transform to DLBCL, PML ... leukemia #CLL #Chronic
Chronic Pancreatitis

Definition: A pathologic fibroinflammatory syndrome of the pancreas in individuals with genetic, environmental, and/or other
Chronic Pancreatitis ... Definition: A pathologic ... fibroinflammatory syndrome ... develop persistent pathologic ... sensitivity) Clinical
Widened Pulse Pressure - Differential Diagnosis and Pathophysiology

Pulse pressure is the difference between the systolic blood
Well-conditioned athletes Pathologic ... disorders - Chronic ... Arteriovenous fistula ... Acute Coronary Syndrome
Myasthenia Gravis Overview

Myasthenia Gravis is an autoimmune disorder of the postsynaptic neuromuscular junction.  Ab to
Clinical Picture ... /Cranial nerve pathology ... Diagnosis - Clinical ... Clinical DX: - ... inhibition - Chronic