8 results
Hypersegmented neutrophil in a case of acute myeloid leukemia.

Dysplastic neutrophils are typically hypolobated but can be
Hypersegmented neutrophil ... Dysplastic neutrophils ... Hypersegmented #neutrophils ... #AML #Clinical ... #Hematology #Pathology
Classic mucosal-dominant Pemphigus Vulgaris. Suprabasal acantholysis leaving behind a “row of tombstones” (i.e. the basal layer
mucosal-dominant Pemphigus Vulgaris ... dominant #Pemphigus #Vulgaris ... #Pathology #Microscopy ... #Dermatology #Clinical
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic #leukemia #APL ... #APML #Pathology ... #Hematology #Clinical
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Differentiation Syndrome in APML ... acute febrile neutrophilic ... Infection (sepsis), PE ... Differentiation #Syndrome #APML ... diagnosis #management #hematology
Pretty good example of Pemphigus Vulgaris. DIF shows intercellular IgG binding throughout entire epidermis. Note there’s
example of Pemphigus Vulgaris ... #Pemphigus #Vulgaris ... #Pathology #Microscopy ... #Dermatology #Clinical
Megaloblastic neutrophils in bone marrow.

So-called "giant bands" and "giant metamyelocytes" (blue circles) are 1.5-2 times the
Megaloblastic neutrophils ... Megaloblastic #neutrophils ... BoneMarrow #Smear #Hematology ... #Pathology #Clinical
SAPHO Syndrome Summary

What?
SAPHO syndrome is a rare chronic inflammatory disorder of bone, joint, and skin characterized
Rheumatic pain Clinical ... acneiform and neutrophilic ... psoriasis, psoriasis vulgaris ... Diagnosis: • A clinical ... diagnosis #management #Dermatology
Myelodysplastic syndromes current treatment algorithm 2018.

From Blood Cancer Journal, Published 24 May 2018

Myelodysplastic syndromes (MDS) are
myeloid leukemia (AML ... cytopenias and AML ... Functional defects in neutrophils ... importance of clinical ... #algorithm #hematology