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Diagnosis and Management of Gastroesophageal Reflux Disease (GERD)

Definition
Presentation
Medical Management
Extraesophageal Symptoms
Long-Term PPI Issues
Diagnosis Algorithm
Refractory GERD
Surgical and Endoscopic
Reflux Disease (GERD ... Symptoms Long-Term PPI ... Algorithm Refractory GERD ... EmoryGastroHep #GERD ... Treatment #Algorithm #Gastroenterology
Gastroesophageal Reflux Disease (GERD) - Summary

GERD: Diagnosis
• Heartburn (substernal burning sensation) and acid regurgitation
• Chest pain
Extraesophageal
indications → PPI ... Therapeutic trial of PPI ... → discontinue PPI ... recurrence → EGD off PPI ... impedance pH) • PPI
Acute Esophageal Necrosis
History: Hematemesis and/or melena (70%), Dysphagia, Epigastric/chest pain, Sepsis
Diagnosis EGD and Biopsy
Differential: Melanosis, Melanoma,
Acute Esophageal ... no NGT, mlVF, PPI ... Braghirol @KBrag_MD #Acute ... diagnosis #management #gastroenterology
Esophageal Necrosis
Etiology:
 - Ischemia and Gastric Outlet Obstruction with GERD may be inciting events
 - Associated
Obstruction with GERD ... 48 hours - IV PPI ... diagnosis #management #gastroenterology
Acute Non-Variceal Upper GI Bleeding
Pre-Endoscopy Management:
 • Hemodynamic resuscitation
 • No routine NG tube
 • Risk
Acute Non-Variceal ... Pre-endoscopy IV PPI ... • High dose IV PPI ... GIBleed #management #gastroenterology
Evidence for Treatment of Acute Esophageal Variceal Bleeding
 • Octreotide (PMID: 11870374) - Endoscopic banding +
for Treatment of Acute ... mortality benefit • PPI ... ) - No role in acute ... ebm #evidence #gastroenterology