21 results
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
AIH-PBC Overlap ... , AIH diagnosis ... Viral) Management ... #Diagnosis #Management ... #Hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... function test, ANA (e.g ... or if a primary hematologic ... #Differential #Diagnosis ... #hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
- Differential Diagnosis ... • Drugs • AIH ... Bile Ducts • PSC ... Others #LFTs #Hepatology ... #Algorithm #Causes
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... - Autoimmune (AIHA ... - Autoimmune (AIHA ... #hematology #anemia
Intraoperative Circulatory Embolus - Guidelines for Crises in Anaesthesia
Causes: thrombus, fat, amniotic fluid, air/gas.
Signs: hypotension, tachycardia,
in Anaesthesia Causes ... over 2 h (>65 kg ... mainstay of initial management ... Intraoperative #Checklist ... #Diagnosis #Management
Cardiac Tamponade - Guidelines for Crises in Anaesthesia
Caused by an accumulation of blood, pus, effusion fluid
effusion fluid or air ... • Diagnostic ... Plan definitive management ... Intraoperative #Checklist ... #Diagnosis #Management
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... Cr, ↓Glucose, ↓PLT ... ) Differential Diagnosis ... Liver #Pregnancy #hepatology ... obstetrics #obgyn #diagnosis
Hemophilia - Diagnosis and Management
Diagnosis:
 • Consistent bleeding history (unless screening for disease in family members
and Management ... normal in mild cases ... hemophilia type (e.g ... Chronic Management ... #hematology
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
Treat primary cause ... abnormalities - PLT ... #Coagulation #diagnosis ... #causes #treatment ... #management #hematology
Intraoperative Sepsis - Guidelines for Crises in Anaesthesia

Severe sepsis (hypotension persisting after initial fluid challenge of
likely underlying cause ... output to further aid ... cultures if possible (eg ... Intraoperative #Checklist ... #Diagnosis #Management