54 results
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
AIH-PBC Overlap ... , AIH diagnosis ... Viral) Management ... #Diagnosis #Management ... #Hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
- Differential Diagnosis ... function test, ANA (e.g ... or if a primary hematologic ... #Differential #Diagnosis ... #hematology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
- Differential Diagnosis ... • Drugs • AIH ... Bile Ducts • PSC ... Others #LFTs #Hepatology ... #Algorithm #Causes
Algorithm for the Evaluation and Management of Sickle Cell Crises
Clinical Manifestations and Management

#Diagnosis #Management #Hematology #SickleCell
of Sickle Cell Crises ... Clinical Manifestations ... and Management ... #Diagnosis #Management ... #Hematology #SickleCell
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes
Intravascular Hemolysis:
 • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... Extravascular Causes ... - Autoimmune (AIHA ... - Autoimmune (AIHA ... #hematology #anemia
Myocarditis
Diagnosis 
• Endomyocardial biopsy (gold standard, rarely performed) 
• Clinical presentation 
• Cardiovascular MRI 
Clinical 
•
Myocarditis Diagnosis ... performed) • Clinical ... gallop • Abnormal ECG ... , echocardiogram ... #Management #Cardiology
Acute-on-Chronic Liver Failure (ACLF) Clinical Guidelines

ACLF = possibly reversible condition in those with CLD (± cirrhosis)
Failure (ACLF) Clinical ... Alcohol-Associated Hepatitis (AAH ... Failure #Cirrhosis #Hepatology ... gastroenterology #management ... #diagnosis
Clinical Diagnosis of Autoimmune Hepatitis
 - Onset of jaundice within prior 8 weeks
 - Ongoing consumption
Clinical Diagnosis ... use assessment (e.g ... laboratory tests (e.g ... Autoimmune #Hepatitis #Diagnosis ... #Hepatology #AIH
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
asymptomatic at diagnosis ... remain subject to clinical ... #Cholangitis #diagnosis ... #management #summary ... #Hepatology
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... Cr, ↓Glucose, ↓PLT ... ) Differential Diagnosis ... Maternal Support - Critical ... Liver #Pregnancy #hepatology