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hematology differential leukemia aplastic chronic cll lymphocytic management mds monoclonal myelodysplasia myelodysplastic paraproteinemias skinrash syndromes ulcerative workup
Skin Ulcers by Etiology - Differential Diagnosis Algorithm Physical: • Trauma • Pressure • Radiation Vascular: • Arterial
Skin Ulcers by Etiology ... Algorithm Physical ... • Sickle Cell Anemia ... ulcerative #skinrash #dermatology ... #Algorithm #causes
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Headaches • Pale skin ... Difficulty breathing • Neutropenia ... and petechiae Causes ... #oncology #hematology ... #diagnosis #management
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Hepatomegaly • Skin ... plaques, nodules, ulcers ... Cytopenias: • Neutropenia ... , anemia, thrombocytopenia ... #workup #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... - infiltrates (anemia ... or functional neutropenia ... CLL -> Invade Skin ... #Oncology #Diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Alpha & Mu) Skin ... Organomegaly+↑RBC/plt ... (-) hemolytic anemia ... #Differential #Diagnosis ... #Oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... just beneath the skin ... Myeloproliferative Disease • Neutropenia ... Myelodysplastic #Syndromes #diagnosis ... #hematology #oncology
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