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hematology management algorithm hepatology aflp alkaline apml chronic classification differentiation disorders elevation endocrinology fatty gastroenterology hodgkins hyperthyroidism leukemia liver lymphoma
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... Diagnosis Algorithm ... Intestine - Other causes ... Bone symptoms - Pain ... - Drugs - Primary
Chronic Abdominal Pain Causes - Differential Diagnosis Framework Many patients with chronic abdominal pain have had prior
Pain Causes - Differential ... Diagnosis Framework ... dysfunction • PSC ... Ovarian CA Diffuse ... #Causes #Differential
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... not required in all ... unclear, or if a primary ... #Diagnosis #Causes ... #Workup #hematology
Acute Fatty Liver of Pregnancy (AFLP) Pathophysiology: • Defect in fetal free fatty acid metabolism products →
= nonspecific (nausea ... , vomiting, abdominal ... pain, headache, ... Cr, ↓Glucose, ↓PLT ... infiltration) Differential
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... , weight loss, abdominal ... + distinctive primary ... #Leukemia #Hematology ... #Oncology #Diagnosis
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Abnormalities in primary ... lesions • Severe pain ... Skin biopsy • Abdominal ... #Causes #dermatology
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
Anterior neck pain ... • Insomnia Primary ... goiter • Toxic diffuse ... hyperthyroidism #causes ... #diagnosis #differential
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Incidence: common in APL ... effusions, weight gain ... initiation • Differential ... fluid overload, PCC ... #oncology
Rhabdomyolysis - Differential Diagnosis Framework and Management Summary Causes of Rhabdomyolysis: • Trauma: - Immobilization - Crush injury - Compartment
Rhabdomyolysis - Differential ... Diagnosis Framework ... Management Summary Causes ... Tachycardia - N/V - Abdominal ... pain Labs:
Vasculitis - Differential Diagnosis Framework When to Consider Vasculitis: • Purpura, ischemic skin lesions • Mononeuritis multiplex • Hematuria, proteinuria,
with GCA or as primary ... Rash, arthritis Primary ... tract, and often causes ... gut involvement, abdominal ... pain and GN Anti-GBM
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