9 results
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
- Differential ... Intestine - Other causes ... Bone symptoms - Pain ... - Drugs - Primary ... #Elevation #Differential
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm 
Tumours
 - See Bone Lesions Scheme
Paget's Disease
 -
Pelvis - Positive Alkaline ... / Ricketts - Diffuse ... Pain/Proximal Muscle ... Phosphate Deficiency Primary ... #Orthopedics #Causes
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... intralobular bile ducts causes ... Labs: • Alkaline ... obstruction • ALP ... bile ducts Differential
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
Platelet Disorders - Differential ... not required in all ... unclear, or if a primary ... Platelet #Disorders #Differential ... #Workup #hematology
Chronic Abdominal Pain Causes - Differential Diagnosis Framework

Many patients with chronic abdominal pain have had prior
Causes - Differential ... Skin changes • Urinary ... dysfunction • PSC ... Ovarian CA Diffuse ... #Differential #
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
infections, bone pain ... -> AML: Blast crises ... + distinctive primary ... #Leukemia #Hematology ... #Oncology #Diagnosis
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Incidence: common in APL ... effusions, weight gain ... initiation • Differential ... fluid overload, PCC ... #oncology
Hyperthyroidism Overview

Clinical Manifestation of Hyperthyroidism:
 • Fatigue
 • Weight loss
 • Heat intolerance
 • Depression, nervousness
Anterior neck pain ... • Insomnia Primary ... goiter • Toxic diffuse ... hyperthyroidism #causes ... #diagnosis #differential
Hodgkin's Lymphoma Overview

Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
accounts for 10% of all ... hemolytic anemia • Pain ... Immunohistochemical studies (to differentiate ... classification #hematology ... #oncology #management