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diagnosis hematology algorithm management workup abdominal alkaline apml cell chronic classification differentiation elevation endocrinology erythematosus fractures fragility gammopathy gap gastroenterology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
- Differential ... not required in all ... unclear, or if a primary ... #Differential # ... #Workup #hematology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... Intestine - Other causes ... Bone symptoms - Pain ... - Drugs - Primary ... #Elevation #Differential
Pathologic / Fragility Fractures - Differential Diagnosis Algorithm Tumours - See Bone Lesions Scheme Paget's Disease -
/ Ricketts - Diffuse ... Pain/Proximal Muscle ... Phosphate Deficiency Primary ... • Bone Marrow Disorder ... #Orthopedics #Causes
Chronic Abdominal Pain Causes - Differential Diagnosis Framework Many patients with chronic abdominal pain have had prior
Causes - Differential ... Skin changes • Urinary ... dysfunction • PSC ... Ovarian CA Diffuse ... #Differential #
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
infections, bone pain ... -> AML: Blast crises ... + distinctive primary ... #Leukemia #Hematology ... #Oncology #Diagnosis
Causes of Petechial Rash - Differential Diagnosis Algorithm Pinpoint areas (less than 2 mm) of hemorrhage, which
Causes of Petechial ... Abnormalities in primary ... Vasculitis - Collagen disorders ... lesions • Severe pain ... #dermatology #physicalexam
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Hematologic disorder ... , or a related disorder ... cells < 10% • Urinary ... #Significance #hematology ... #diagnosis #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Incidence: common in APL ... effusions, weight gain ... initiation • Differential ... fluid overload, PCC ... #oncology
Hyperthyroidism Overview Clinical Manifestation of Hyperthyroidism: • Fatigue • Weight loss • Heat intolerance • Depression, nervousness
Anterior neck pain ... • Insomnia Primary ... goiter • Toxic diffuse ... hyperthyroidism #causes ... #diagnosis #differential
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
permanent alopecia Differential ... the context of primary ... pneumonitis • Diffuse ... Arthritis: • Joint pain ... enteropathy, and diffuse
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