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diagnosis hematology algorithm localized lymphadenopathy workup abdominal allergy cell chronic diffuse disorders gastroenterology ileitis leukemia monoclonal pain paraproteinemias plasmacytoma platelet
Causes of Diffuse and Localized Lymphadenopathy - Differential Diagnosis Algorithm • Reactive (Inflammatory / Infectious) •
Causes of Diffuse ... ) #Diffuse #Focal ... Lymphadenopathy #LAD ... #Differential # ... #Hematology #Oncology
Causes of Localized Lymphadenopathy - Differential Diagnosis Algorithm Cervical: - Anterior • Infection
Causes of Localized ... #Localized #Focal ... Lymphadenopathy #LAD ... #Differential # ... #Hematology #Oncology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... HCV testing - Lab ... . pylori test (GI ... unclear, or if a primary ... #Workup #hematology
Causes of ileitis beyond Crohn’s disease and infections include systemic disorders -spondyloarthropathies, vasculitides, ischemia, and amyloidosis
Causes of ileitis ... medications may lead ... www.ncbi.nlm.nih.gov/pmc ... #Ileitis #Differential ... #Table
Chronic Abdominal Pain Causes - Differential Diagnosis Framework Many patients with chronic abdominal pain have had prior
- Differential ... dysfunction • PSC ... mesenteric ischemia • GI ... intolerance • SIBO Focal ... #Differential #
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Organomegaly+↑RBC/plt ... Scleromyxedema (CNS+GI ... Amyloidosis (CVS+PNS+GI ... #Monoclonal #Differential ... #Diagnosis #Oncology
Approach to Elevated Tryptase - Differential Diagnosis Framework The DDx of elevated tryptase can be broken down
Elevated Tryptase - Differential ... • CKD/ESRD & CAD ... • Eosinophilic GI ... 3rd pass = Primary ... #Diagnosis #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... -> AML: Blast crises ... + distinctive primary ... #Leukemia #Hematology ... #Oncology #Diagnosis
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Less common - GI ... except for the primary ... UPEP, Serum IFE, FLC ... with improved local ... #Plasmacytoma #Oncology
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