14 results
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Severe Acute Liver Injury ... Drug-Induced liver injury ... - Autoimmune ... Acute #Causes #Differential ... #Hepatology #Diagnosis
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
of Acute Liver Injury ... - Differential ... Diagnosis Hepatocellular ... Other: NAFLD, Autoimmune ... #Differential #
Hepatomegaly - Differential Diagnosis Algorithm
Malignant
 • Primary Carcinoma
 • Metastases
 • Lymphoma
 • Leukemia
 • Polycythemia
Hepatomegaly - Differential ... Diagnosis Algorithm ... Non-Malignant • Fatty ... • Autoimmune ... #Causes #Hepatology
Common Etiologies of Cirrhosis

Inflammation

 - Hepatitis B (15 percent)

 - Hepatitis C (47 percent)

 - Schistosomiasis
Schistosomiasis - Autoimmune ... - Nonalcoholic fatty ... 14 percent) #Diagnosis ... #Differential # ... Hepatology #Cirrhosis
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
Pregnancy (AFLP) Pathophysiology ... Cr, ↓Glucose, ↓PLT ... infiltration) Differential ... Diagnosis: Viral ... Hepatitis, Preeclampsia
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... : Autoimmune hepatitis ... #hepatitis #differential ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Differential Diagnosis ... • Infections: Hepatitis ... Other: NAFLD, Autoimmune ... Diagnosis #hepatology ... Transaminitis #LFTs #hepatitis
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Autoimmune Hepatitis ... pattern of liver injury ... , AIH diagnosis ... BryanCUlrich #Autoimmune ... #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Liver Enzymes - Differential ... Diagnosis Algorithm ... • Ischemia • Autoimmune ... Bile Ducts • PSC ... • Alcoholic hepatitis
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Pathophysiology ... Diagnosis: • ... bile ducts Differential ... Viral hepatitis, ... #workup #hepatology