12 results
Causes of Severe Acute Liver Injury
 - Ichemic hepatitis
 - Acute biliary obstruction
 - Drug-Induced liver
Severe Acute Liver Injury ... Drug-Induced liver injury ... - Autoimmune ... Acute #Causes #Differential ... #Hepatology #Diagnosis
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
of Acute Liver Injury ... - Differential ... Diagnosis Hepatocellular ... Other: NAFLD, Autoimmune ... #Differential #
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
- Differential ... Diagnosis Algorithm ... : Autoimmune hepatitis ... #hepatitis #differential ... #hepatology
Hepatocellular Liver Injury - Differential Diagnosis Framework:
Liver Injury → liver test abnormalities without evidence of liver
Differential Diagnosis ... • Infections: Hepatitis ... Other: NAFLD, Autoimmune ... Diagnosis #hepatology ... Transaminitis #LFTs #hepatitis
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
Autoimmune Hepatitis ... pattern of liver injury ... , AIH diagnosis ... BryanCUlrich #Autoimmune ... #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Liver Enzymes - Differential ... Diagnosis Algorithm ... • Ischemia • Autoimmune ... Bile Ducts • PSC ... • Alcoholic hepatitis
Acute Fatty Liver of Pregnancy (AFLP)
Pathophysiology:
 • Defect in fetal free fatty acid metabolism products →
, ↑Tbili/Dbili/AP ... Cr, ↓Glucose, ↓PLT ... infiltration) Differential ... Diagnosis: Viral ... Hepatitis, Preeclampsia
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Pathophysiology ... Diagnosis: • ... bile ducts Differential ... Viral hepatitis, ... #workup #hepatology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
Cirrhosis, ETOH, autoimmune ... hepatitis, PBC, ... PSC, Viral hepatitis ... #ProteinGap #differential ... #diagnosis #hematology
Causes of Petechial Rash - Differential Diagnosis Algorithm

Pinpoint areas (less than 2 mm) of hemorrhage, which
Petechial Rash - Differential ... Diagnosis Algorithm ... Palpable Rash: - Autoimmune ... RA, Sjogren's, GPA ... • Serology for hepatitis