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diagnosis hematology workup algorithm alkaline biliary cholangitis cirrhosis disorders elevation gap globulin icl idiopathic leukemia lymphocytopenia lymphopenia nonpalpable oncology palpable
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
) Elevation - Differential ... Highest • Bone • Liver ... Intestine - Other causes ... - Drugs - Primary ... Diagnosis #Algorithm #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Platelet Disorders - Differential ... : INR/PT, aPTT(liver ... not required in all ... unclear, or if a primary ... #Workup #hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
intralobular bile ducts causes ... obstruction • ALP ... or higher • Liver ... bile ducts Differential ... diagnosis #workup #hepatology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
Purpura - Differential ... /Quantity: • Primary ... : ITP • Secondary ... deficiency • Liver ... #Diagnosis #hematology
Idiopathic CD4 Lymphopenia (ICL) / Lymphocytopenia DIAGNOSTIC CRITERIA FOR ICL • Persistent CD4 T-cell lymphopenia •
NO underlying primary ... or secondary immune ... ICL #diagnosis #hematology ... #Differential # ... Causes #lymphocytopenia
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
-> AML: Blast crises ... count • ↓Hg & PLT ... + distinctive primary ... bone marrow and secondary ... #Leukemia #Hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Castleman disease • AL ... Sarcoidosis) • Liver ... gastric tumors • Hematology ... Gap #ProteinGap #differential ... #diagnosis #hematology
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