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diagnosis algorithm lfts pbc primary causes cholangitis differentiation elevated hematology hepatitis injury liver liverenzymes liverfunctiontests oncology syndrome transaminitis treatment workup
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... Congenital, Others, Cirrhosis ... - CBD stone, Biliary ... Algorithm #diagnosis #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... Cirrhosis (PBC) ... bile ducts Differential ... #Cirrhosis #PBC ... diagnosis #workup #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
disease US — Normal ... Bile Ducts • PSC ... Infiltrative • Cirrhosis ... Duct Stone • Biliary ... Others #LFTs #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Liver Injury - Differential ... function may be abnormal ... hepatitis: < 1 • Cirrhosis ... injury #hepatitis #differential ... diagnosis #algorithm #hepatology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
Differentiation Syndrome in APML ... initiation • Differential ... 500 mg QD until normal ... fluid overload, PCC ... #diagnosis #management
Primary Biliary Cirrhosis - Management A. Initiate therapy - Initiate 1st line therapy with UDCA (13-15
Primary Biliary ... Cirrhosis - Management ... 1.5x ULN and/or abnormal ... #Cirrhosis #Management ... #Treatment #hepatology
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