15 results
Evaluation of Lymphadenopathy - Localized vs Generalized #Diagnosis #EM #IM #Honc #Lymphadenopathy #Localized #Generalized #Infectious #Malignancy
Evaluation of Lymphadenopathy ... Generalized #Diagnosis #EM ... Differential #Algorithm #Ddxof ... #Oncology
Evaluation and Management of Pediatric Fever #Diagnosis #Management #EM #Peds #Fever #Workup #Evaluation #Discharge #Admission #Algorithm
Evaluation and Management ... of Pediatric Fever ... Diagnosis #Management #EM ... #Peds #Fever #Workup ... Admission #Algorithm #Ddxof
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
Headaches, bone pain, fever ... Significant ↓ PLT ... count • ↓Hg & PLT ... Lymphadenopathy • HSM • Fevers ... Leukemia #Hematology #Oncology
Serious Bacterial Illness (SBI):
1) UTI and pyelonephritis
Most common cause of SBI
Accounts for 3-8% of uncharacterized fevers
Female
uncharacterized fevers ... Consider BCx, CSF evaluation ... Diagnosis #Peds #EM ... Classification #Fever ... SeriousBacterialIllness #Ddxof
Differential Diagnosis of Hypoglycemia
Evaluation of Hypoglycemia
Patients with known diabetes who are not systemically ill and can
of Hypoglycemia Evaluation ... blood cultures - ECG ... antibodies #Diagnosis #EM ... #Hypoglycemic #Ddxof
Algorithm for Evaluation of Suspected Pulmonary Embolism #Diagnosis #EM #IM #PCC #PulmonaryEmbolism #Pulmonary #Embolism #DDimer #CTA
Algorithm for Evaluation ... Embolism #Diagnosis #EM ... #IM #PCC #PulmonaryEmbolism ... CTA #Algorithm #Ddxof
Hodgkin's Lymphoma vs Non-Hodgkin's Lymphoma - Comparison

Hodgkin's Lymphoma:
 • Epidemiology: young adults 20-30, older 50-70
 •
Immunosuppression (e.g ... - Pel-Ebstein fever ... Autoimmune diseases (e.g ... Malignancies (eg ... NonHodgkins #comparison #oncology
Hemophagocytic Lymphohistiocytosis (HLH)
Pathophysiology: Triggering factor (infection,...)→Activation of CD8 T cells (IFN-y) → Excessive activation of macrophages
Activation of CD8 T cells ... • Clinical: fever ... Cytopenia +++ (Plt ... lymphoma, B-cell ... inhibitors under evaluation
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
• Induce blast cell ... Prednisone 5mg/kg ... Subacute-Acute: • Common: fever ... fluid overload, PCC ... management #hematology #oncology
Evaluation of Leukocytosis:
The term 'leukocyte' applies to any cells within the myeloblast, monoblast, & lymphoid lineages.
Include
Evaluation of Leukocytosis ... applies to any cells ... killer cells). ... -100,000 per (e.g ... neutropenia: typhoid fever