5 results
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Primary Biliary ... Pathophysiology ... Labs: • Alkaline ... #diagnosis #workup ... #hepatology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism
AST and ALT:
 • AST: liver
CAST) • ALT: primarily ... within bile duct cells ... #Bilirubin #Hepatology ... #Pathophysiology ... #Diagnosis #LFTs
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
- infiltrates (anemia ... + distinctive primary ... Fibrinolysis & DIC ... #Leukemia #Hematology ... #Oncology #Diagnosis
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
protein C and S Pathophysiology ... Schistocytes, helmet cells ... Treatment: • Treat primary ... #Coagulation #diagnosis ... treatment #management #hematology
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
Diagnosis? ... except for the primary ... • No CRAB - no anemia ... UPEP, Serum IFE, FLC ... #Workup #Hematology