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diagnosis differential algorithm pbc alkaline alp causes cirrhosis phosphatase psc workup acute alkphos astalt bilirubin chemistry comparison dili disorders druginduced
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis #pathophysiology #pbc #psc #hepatology #comparison
Cholestatic Liver ... Biliary Cirrhosis ... Cholangitis ... #pathophysiology ... #pbc #psc #hepatology
Causes of Severe Acute Liver Injury - Ichemic hepatitis - Acute biliary obstruction - Drug-Induced liver
of Severe Acute Liver ... Injury - Ichemic ... Hemochromatosis - Primary ... biliary cholangitis ... #Differential #Hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm ALP: - Enzymes that catalyze hydrolysis of organic phosphate
Highest • Bone • Liver ... - Drugs - Primary ... biliary Cholangitis ... - Other biliary ... Diagnosis #Algorithm #hepatology
Liver Function Test (LFTs) Elevation AST - Cardiac and skeletal muscle, kidney, brain ALT - More specific for
(LFTs) Elevation ... ALP - Biliary ... Hepatocellular injury ... #FunctionTest #LFTs ... #diagnosis #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... Pathophysiology ... or higher • Liver ... #PBC #cholangitis ... diagnosis #workup #hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm DILI suspicion Features toxic aetiology: Skin involvement, Kidney injury,
obstruction, Primary ... biliary cholangitis ... , Primary sclerosing ... cholangitis Consider ... #Algorithm #hepatology
Primary Biliary Cirrhosis - Pathophysiology Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish Epigentics Risk
Primary Biliary ... Cirrhosis - Pathophysiology ... T-cell mediated BEC injury ... #Primary #Biliary ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Acute Liver Injury ... , Biliary Stricture ... Bilirubin - +/- elevation ... Enzyme Elevation ... diagnosis #algorithm #hepatology
The 6 C’s of Primary Sclerosing Cholangitis (PSC) PSC is a chronic, cholestatic, immune-mediated disease characterized by
The 6 C’s of Primary ... to multi-focal biliary ... colorectal and hepato-biliary ... #Primary #Sclerosing ... management #summary #Hepatology
Liver Chemistry Tests - AST, ALT, Alkaline Phosphatase and Bilirubin Metabolism AST and ALT: • AST: liver
CAST) • ALT: primarily ... hepatocyte - Elevation ... AlkPhos #Bilirubin #Hepatology ... #Pathophysiology ... #Diagnosis #LFTs
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