20 results
Cholestatic Liver Disease: Primary Biliary Cirrhosis vs Primary Sclerosing Cholangitis

#pathophysiology #pbc #psc #hepatology #comparison
Liver Disease: Primary ... Biliary Cirrhosis vs Primary ... Cholangitis #pathophysiology ... #pbc #psc #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Alkaline Phosphatase ... - Drugs - Primary ... biliary Cholangitis (PBC ... Infiltrative diseases - PSC ... Diagnosis #Algorithm #hepatology
Primary Biliary Cirrhosis (PBC) - Summary

PBC Epidemiology:
 • Female:Male 9:1
 • Common European descent
 • Age:
Cirrhosis (PBC) ... - Summary PBC ... Pathophysiology ... Labs: • Alkaline ... diagnosis #workup #hepatology
Primary Biliary Cirrhosis - Pathophysiology
Environmental Risk Factors: Geographic location, Smoking, Microbial triggers, Xenobiotics, Nail polish
Epigentics Risk
Primary Biliary ... relative with PBC ... Cholestasis #PBC ... #Primary #Biliary ... #hepatology
Algorithm for the Diagnosis of Primary Biliary Cholangitis (PBC). 

US, ultrasound; MRCP, magnetic resonance cholangiopancreatography; ALP,
the Diagnosis of Primary ... Biliary Cholangitis (PBC ... cholangiopancreatography; ALP, alkaline ... #Cholangitis #PBC ... Algorithm #Diagnosis #Hepatology
The 6 C’s of Primary Sclerosing Cholangitis (PSC)
PSC is a chronic, cholestatic, immune-mediated disease characterized by
The 6 C’s of Primary ... liver disease management ... #Primary #Sclerosing ... Cholangitis #diagnosis #management ... #summary #Hepatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Pancytopenia: • ↓ RBC ... • ↓ WBC • ↓ ... PLT • Reticulocyte ... #oncology #hematology ... #diagnosis #management
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Low Alkaline Phosphatase ... • Pernicious anemia ... collection with EDTA Pathophysiology ... • Elevation of urinary ... Hyophosphatasia #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
for decreased PLT ... for decreased PLT ... changes), high MCV anemia ... unclear, or if a primary ... Causes #Workup #hematology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
ATRA treatment Pathophysiology ... if high risk if WBC ... fluid overload, PCC ... APML #diagnosis #management ... #hematology #oncology