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hematology differential causes algorithm hemolysis oncology intravascular biliary cell cholangitis coagulation dermatology dic disorders disseminated extravascular gap globulin leukemia maha
Hemolytic Anemia - Hemolysis Diagnostic Workup Infographic by: Howard Ong #Hemolysis #Hemolytic #Anemia #Algorithm #MAHA #TTP #Diagnosis #Workup
Hemolytic Anemia ... - Hemolysis Diagnostic ... #Hemolytic #Anemia ... Algorithm #MAHA #TTP ... #Diagnosis #Workup
Hemolysis - Diagnostic Algorithm and Causes Increased red cell production: • Increased Reticulocytosis/polychromasia • Erythroid
Hemolysis - Diagnostic ... Urobilinogen • + urinary ... #Hemolytic #Anemia ... Differential #Causes #Workup ... #Hematology #Diagnosis
Diagnostic Framework for Hemolysis - Intravascular vs Extravascular Causes Intravascular Hemolysis: • Mechanical Trauma (Microangiopathic hemolytic anemia):
Diagnostic Framework ... anemia): ... thrombocytopenic purpura (TTP ... usually IgM) (e.g. primary ... #hematology #anemia
Hemolytic Anemia - Differential Diagnosis Algorithm • Sickle cells - Consider sickle cell disease (diverse genotypes):
Hemolytic Anemia ... - Differential Diagnosis ... thrombocytopenia - DIC, TTP ... #Anemia #Differential ... #workup #hematology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... Cirrhosis (PBC) ... Pathophysiology ... #diagnosis #workup ... #hepatology
TTP - Laboratory Evaluation for Thrombotic Thrombocytopenic Purpura Activity of von Willebrand factor-cleaving protease activity - A
TTP - Laboratory ... result in severe anemia ... anemia Indirect ... impairment #TTP ... #Workup #Hematology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
and Workup History ... changes), high MCV anemia ... unclear, or if a primary ... Refractory ITP, ... #hematology
Purpura - Differential Diagnosis Framework Non-blanchable, dark red to purple, hemorrhagic skin lesions that result from leakage
- Differential Diagnosis ... /Quantity: • Primary ... /HUS - Hemolytic ... anemia - Splenomegaly ... Defects: • DIC, TTP
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
protein C and S Pathophysiology ... • TMA’s (HUS/TTP ... Schistocytes - MAHA: TTP ... Treatment: • Treat primary ... #Coagulation #diagnosis
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Organomegaly+↑RBC/plt ... • Coombs (-) hemolytic ... anemia due to cold ... Paraproteinemias #Hematology ... #Differential #Diagnosis
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