9 results
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
(Kcentra) - Heparin ... Protamine sulfate - Dabigatran ... anticoagulation #doac ... #noac #pharmacology ... #hematology #reversal
NOAC / DOAC Pharmacology and Prescribing Cheat Sheet
Novel (or Direct) Oral Anti-Coagulants
 • Rivaroxaban
 • Apixaban
NOAC / DOAC Pharmacology ... • Apixaban • Dabigatran ... #NOAC #DOAC #Pharmacology ... #Prescribing #hematology ... #management #Direct
Oral anticoagulant dosing and bridging for VTE

- Dr. Joseph Shatzel @Clotmaster 

#VTE #DOAC #Bridging #Dosing #Oral
Clotmaster #VTE #DOAC ... #Bridging #Dosing ... Anticoagulation #Dabigatran ... #Loading #DVT #Pharmacology ... #Hematology
Anticoagulant specific factor inhibition. 

#anticoagulation #clotting #INR #heparin #LMWH #NOAC #warfarin #coumadin #rivaroxaban  #Xarelto #apixaban
clotting #INR #heparin ... #LMWH #NOAC #warfarin ... apixaban #Eliquis #dabigatran ... #Pradaxa #management ... #pharmacology #
Heparin, Fondaparinux, and Novel Oral Anticoagulants - Pathophysiology

Anticoagulation with parenteral (intravenous or subcutaneous) and oral anticoagulants
Heparin, Fondaparinux ... accelerates the bridging ... #Pharmacology #Pathophysiology ... #UFH #DOAC #Dabigatran ... #Fondaparinux #NOAC
Summary table of the mechanism of action, side effect and contraindications of commonly used anti-coagulation drugs.
Molecular Weight Heparin ... ) inhibitors - Dabigatran ... anticoagulation #pharmacology ... #medications #doac ... comparison #table #management
Anticoagulant Bridging

 • Switching from LMWH
 • Switching from UFH
 • Switching from DOAC to Warfarin
Anticoagulant Bridging ... Switching from DOAC ... from Warfarin to DOAC ... anticoagulation #pharmacology ... #management #hematology
DOAC Reversal
Emergency surgery or urgent procedure
Stop anticoagulant treatment; volume resuscitation and transfusion as needed
Antidotes:
 • Apixaban,
DOAC Reversal Emergency ... modified factor Xa • Dabigatran ... not available #DOAC ... anticoagulant #hematology ... #management #pharmacology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
Diagnosis and Management ... complex → plt activation ... hypercoagulable state and plt ... , Bivalirudin, DOAC ... #Treatment #Hematology