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hematology oncology anticoagulant aplastic cyp3a4 diagnosis inducers inhibitors interactions noac oral pglycoprotein reversal table
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓) of cytochrome p450 CYP3A4 and P-glycoprotein. DOACs are substrates
) Cancer-treatment ... Dabigatran has moderate ... inducers #inhibitors #Chemotherapy ... #Oncology #Hematology ... Interactions #Table #Pharmacology
DOAC Reversal Emergency surgery or urgent procedure Stop anticoagulant treatment; volume resuscitation and transfusion as needed Antidotes: • Apixaban,
DOAC Reversal Emergency ... anticoagulant treatment ... modified factor Xa • Dabigatran ... anticoagulant #hematology ... #management #pharmacology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Cytotoxic drugs/Chemotherapy ... • ↓ WBC • ↓ PLT ... Treatment: ... #oncology #hematology ... #diagnosis #management
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