13 results
diagnosis hematology algorithm management causes lfts monoclonal aplastic apml bandemia cbc cholangitis cirrhosis classification differentiation elevated gammopathy gap globulin hepatitis
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Tests - Differential ... - CBD stone, Biliary ... LFTs #Elevated #Abnormal ... Algorithm #diagnosis #hepatology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
Primary Biliary ... Pathophysiology ... No extrahepatic biliary ... bile ducts Differential ... diagnosis #workup #hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm Severe ALT > 15x ULN • Viral • Drugs/Toxins •
Liver Enzymes - Differential ... disease US — Normal ... Bile Ducts • PSC ... Duct Stone • Biliary ... Others #LFTs #Hepatology
Acute Liver Injury - Differential Diagnosis Algorithm Vascular Causes of Acute Liver Injury: • Hepatic vein:
Liver Injury - Differential ... Extrahepatic - Biliary ... function may be abnormal ... injury #hepatitis #differential ... diagnosis #algorithm #hepatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... syndrome (MDS) (normal ... megakaryocytes and a normal ... • ↓ WBC • ↓ PLT ... #oncology #hematology
Bandemia Overview Normal: < 1% Clinically significant: > 10% Band neutrophils are slightly less mature than segmented neutrophils and
) Differential ... bacteremia • Abnormal ... #differential # ... neutrophil #WBC #CBC #hematology ... #pathophysiology
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
presence of either abnormal ... No evidence of anemia ... insufficiency, Anemia ... Light-Chain MGUS: • Abnormal ... #diagnosis #oncology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... initiation • Differential ... 500 mg QD until normal ... fluid overload, PCC ... #oncology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
cell types are abnormal ... low and appear abnormal ... blood count with differential ... Syndromes #diagnosis #hematology ... #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Organomegaly+↑RBC/plt ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Monoclonal #Differential ... #Diagnosis #Oncology
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