14 results
diagnosis hematology differential management aplastic causes leukemia monoclonal apml biliary cell cholangitis chronic cirrhosis classification cll differentiation disorders gap globulin
Aplastic Anemia Summary • Definition • Pathophysiology • DDx: AA vs Hypocellular MDS • Expectation •
Aplastic Anemia ... Definition • Pathophysiology ... #Aplastic #Anemia ... #diagnosis #oncology ... #hematololgy
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Monoclonal Gammopathy ... No evidence of anemia ... insufficiency, Anemia ... MGUS #Monoclonal #Gammopathy ... #diagnosis #oncology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
) - Summary PBC ... 30-65 years PBC ... Pathophysiology ... cholangitis #diagnosis #workup ... #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... for decreased PLT ... changes), high MCV anemia ... Diagnosis #Causes #Workup ... #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Immune Aplastic Anemia ... • ↓ WBC • ↓ PLT ... #oncology #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... or polyclonal gammopathy ... of Monoclonal Gammopathy ... gastric tumors • Hematology ... Thalassemia, Sickle cell anemia
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... fluid overload, PCC ... diagnosis #management #hematology ... #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... Leukemia #diagnosis #workup ... #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Significant ↓ PLT ... - infiltrates (anemia ... count • ↓Hg & PLT ... #Leukemia #Hematology ... #Oncology #Diagnosis
Anemia of Hospitalization - Pathophysiology Why does the Hgb/Hct drop in the first two days during hospitalization? Interestingly,
- Pathophysiology ... www.ncbi.nlm.nih.gov/pmc ... www.ncbi.nlm.nih.gov/pmc ... phlebotomy/ blood work ... Hospitalization #causes #pathophysiology
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