16 results
diagnosis hematology differential management leukemia aplastic causes chronic cll lymphocytic mgus apml biliary cell cholangitis cirrhosis classification differentiation disorders gammopathies
Aplastic Anemia Summary • Definition • Pathophysiology • DDx: AA vs Hypocellular MDS • Expectation •
Aplastic Anemia ... Definition • Pathophysiology ... #Aplastic #Anemia ... #diagnosis #oncology ... #hematololgy
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
No evidence of anemia ... insufficiency, Anemia ... increased kappa FLC ... #Significance #hematology ... #diagnosis #oncology
Multiple Myeloma and Monoclonal Gammopathies C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN R
Multiple Myeloma and Monoclonal ... 40 ml/min A - Anemia ... if this is is monoclonal ... MGUS #diagnosis #hematology ... #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Can Feature A Monoclonal ... Organomegaly+↑RBC/plt ... (-) hemolytic anemia ... Paraproteinemias #Hematology ... #Diagnosis #Oncology
Primary Biliary Cirrhosis (PBC) - Summary PBC Epidemiology: • Female:Male 9:1 • Common European descent • Age:
) - Summary PBC ... 30-65 years PBC ... Pathophysiology ... cholangitis #diagnosis #workup ... #hepatology
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Diagnosis and Workup ... for decreased PLT ... changes), high MCV anemia ... Diagnosis #Causes #Workup ... #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
5) Symptoms of anemia ... marrow failure with anemia ... fludarabine) 3) Monoclonal ... Lymphocytic #Leukemia #oncology ... #hematology #hemeonc
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... • Aplastic anemia ... Immune Aplastic Anemia ... • ↓ WBC • ↓ PLT ... #oncology #hematology
Differentiation Syndrome in APML Epidemiology: • Incidence: common in APL (2-48% depending on the study) • Triggers:
ATRA treatment Pathophysiology ... fluid overload, PCC ... diagnosis #management #hematology ... #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
• Neutropenia, anemia ... Leukemia #diagnosis #workup ... #oncology #hematology
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