11 results
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
plateletcount), peripheral blood ... smear, HIV/HCV ... changes), high MCV anemia ... not required in all ... #Workup #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... • Lymphoid (ALL ... Pelger-Huet, Macrocytic anemia ... - Amy Chung, MD ... #Disorders #hematology
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Differential Diagnosis Algorithm ... Blood Loss ... Normochromic RBCs on Smear ... Spherocytes on Smear ... #Causes #Hematology
Causes of Anemia with elevated Mean Corpuscular Volume (MCV) - Differential Diagnosis Algorithm
Normal Blood Smear
 •
Causes of Anemia ... Differential Diagnosis Algorithm ... Normal Blood Smear ... • Small Bowel Disorder ... #Causes #Hematology
Acute promyelocytic leukemia (blood). Typical morphologic features are bilobed ("butterfly") nuclei with dispersed chromatin, subtle to
promyelocytic leukemia (blood ... features in most cases ... Kyle Bradley, MD ... APML #Pathology #Hematology ... #Clinical #Smear
Hematology Algorithms 

Anemia is described as a reduction in the proportion of the red blood cells.
Hematology Algorithms ... proportion of the red blood ... a decrease in all ... well as varying clinical ... These causes could
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
smear or on bone ... -> AML: Blast crises ... - infiltrates (anemia ... • Peripheral smear ... more aggressive form
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... caused by blood ... Peripheral Smear ... involve one, two, or all ... smear • Bone marrow
Low Alkaline Phosphatase - Hypophosphatasia 

Is Low Alkaline Phosphatase Of Clinical Importance?

ALP enzyme- Discovered in 1923
Low
Phosphatase Of Clinical ... Adult form: Less ... • Pernicious anemia ... deficiency • blood ... Hyophosphatasia #hepatology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
Clinical Presentation ... and petechiae Causes ... • ↓ WBC • ↓ PLT ... result from low blood ... #oncology #hematology