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hematology diagnosis leukemia chronic cll lymphocytic microscopy workup analysis aplastic bloodsmear borrelia causes cell classification coagulation dic disseminated hemeonc hodgkins
Peripheral Blood Smear Analysis Hypochromia Megaloblastic Anemia Schistocytes: Microangiopathic hemolytic anemia (e.g. DIC, TTP, HUS) Microspherocytes: Autoimmune hemolytic anemia Sickled red
Peripheral Blood ... Smear Analysis ... Sickled red cells ... #hematology #microscopy ... interpretation #clinical
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
smear or on bone ... - infiltrates (anemia ... • Peripheral smear ... more aggressive form ... #Oncology #Diagnosis
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Clinical Presentation ... • ↓ WBC • ↓ PLT ... result from low blood ... #oncology #hematology ... #diagnosis #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Peripheral Smear ... syndromes with single-lineage ... smear • Bone marrow ... Syndromes #diagnosis #hematology ... #oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
• Peripheral smear ... immunophenotype Clinical ... 5) Symptoms of anemia ... Lymphocytic #Leukemia #oncology ... #diagnosis #management
Borrelia recurrentis on Peripheral Blood Smear 23M Somali refugee recently arrived w/severe abd pain, confusion and fever
Smear 23M Somali ... 12.5, WBC 14, Plt ... The table below ... be treated in a single ... microscopy #pathology #clinical
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... • Peripheral smear ... Lymphocytosis: Absolute blood ... • Neutropenia, anemia ... diagnosis #workup #oncology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
ABO incompatible blood ... organ damage Clinical ... • Peripheral smear ... causes #treatment #management ... #hematology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Hodgkin Lymphoma - Clinical ... Weight loss • Anemia ... Immune hemolytic anemia ... Workup: • Full Blood ... #oncology #management
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
can present as a single ... plasmacytoma) Clinical ... • No CRAB - no anemia ... UPEP, Serum IFE, FLC ... #Plasmacytoma #Oncology
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