12 results
Overall Approach to Anemia - Differential Diagnosis Algorithm

Blood Loss
 • Acute Bleed - Normocytic / Normochromic
Normochromic RBCs on Smear ... • Chronic Bleed ... • Anemia of Chronic ... Spherocytes on Smear ... Algorithm #Causes #Hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm 
Acute
 • Myloid (AML) - CD13, CD33, CD34,
T-cell - CD7, CD3 Chronic ... Pelger-Huet, Macrocytic anemia ... o CML - bcr-able ... o Other bcr-able ... #hematology #Markers
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup
History:
 - Prior platelet count, family
peripheral blood smear ... changes), high MCV anemia ... or if a primary hematologic ... dysplasia on the smear ... Causes #Workup #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary
Overview: 
 • Most common leukemia in adults
 • Disorder of
Chronic Lymphocytic ... leukemia in adults • Disorder ... • Peripheral smear ... immunophenotype Clinical ... Leukemia #oncology #hematology
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... - infiltrates (anemia ... • Peripheral smear ... more aggressive form ... #Leukemia #Hematology
Cold Agglutinin Disease

3 Types of Cold Sensitive Antibodies:
  1. Cold Agglutinins (CAD)
  2. Donath-Landsteiner
Viral Infection Clinical ... • Symptoms of anemia ... • hemolytic anemia ... IgM) • Blood smear ... #hematology #diagnosis
Chronic Lymphocytic Leukemia - Summary

Cancer affecting lymphocytes/Mature B cell neoplasm
 • Lymphocytes accumulate in large numbers
Orange or Hep C Clinical ... • Peripheral smear ... lymphoproliferative disorders ... • Neutropenia, anemia ... workup #oncology #hematology
Common Variable Immunodeficiency (CVID)

What?
CVID: Immunodeficiency disorder with hypogammaglobulinemia -> increased infection risk secondary to impaired B-cell
Immunodeficiency disorder ... to 8 years Clinical ... Autoimmunity • Chronic ... autoimmune hemolytic anemia ... hypogammaglobulinemia #immunology #hematology
Myelodysplastic Syndromes (MDS)

What?
Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
are a group of disorders ... Peripheral Smear ... Marrow Failure • Chronic ... Peripheral blood smear ... Syndromes #diagnosis #hematology
SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Malignancy (e.g. hematologic ... lymphoproliferative syndrome Clinical ... • Anemia of inflammation ... with Lupus: • Chronic