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diagnosis oncology management cll lymphocytic alkaline alp aplastic causes coagulation dic disseminated erythematosus hemeonc hyophosphatasia intravascular low lupus mds myelodysplasia
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... Chronic leukemia ... - infiltrates (anemia ... • Peripheral smear ... #Hematology #Oncology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
Chronic Lymphocytic ... • Peripheral smear ... immunophenotype Clinical ... 5) Symptoms of anemia ... #oncology #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic ... Orange or Hep C Clinical ... • Peripheral smear ... • Neutropenia, anemia ... workup #oncology #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... Clinical Presentation ... virus (EBV) • Leukemia ... • ↓ WBC • ↓ PLT ... #oncology #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
promyelocytic leukemia ... organ damage Clinical ... • Peripheral smear ... abnormalities - PLT ... treatment #management #hematology
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
Peripheral Smear ... Marrow Failure • Chronic ... Myelogenous Leukemia ... • Hairy Cell Leukemia ... Syndromes #diagnosis #hematology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... Adult form: Less ... thigh bones -> chronic ... • Pernicious anemia ... Hyophosphatasia #hepatology
SLE (Systemic Lupus Erythematosus) Suspect: Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and
) Suspect: Clinical ... Malignancy (e.g. hematologic ... • Anemia of inflammation ... with Lupus: • Chronic ... Hodgkin lymphoma and leukemia
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