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diagnosis oncology management chronic cll lymphocytic pathology rouleaux alkaline alp aplastic blood causes coagulation dic disseminated hemeonc hyophosphatasia intravascular low
Plasma cell leukemia with extensive rouleaux formation. Aggressive disease & patients typically younger than other forms
Plasma cell leukemia ... extensive rouleaux formation ... #rouleaux #formation ... #Clinical #Smear ... #Hematology #Pathology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
peripheral blood smear ... - infiltrates (anemia ... • Peripheral smear ... more aggressive form ... #Hematology #Oncology
Autoagglutination should also be distinguished from “Rouleaux formation” wherein normal blood tends to form stacks on
from “Rouleaux formation ... blood tends to form ... #Clinical #Pathology ... #Blood #Smear # ... #Hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
• Peripheral smear ... immunophenotype Clinical ... 5) Symptoms of anemia ... marrow failure with anemia ... #oncology #hematology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Chronic Lymphocytic Leukemia ... Orange or Hep C Clinical ... • Peripheral smear ... • Neutropenia, anemia ... workup #oncology #hematology
Disseminated Intravascular Coagulation (DIC) Overview Increased Clotting and Consumption of Clotting Factors Findings: • Bleeding • Recent history
promyelocytic leukemia ... organ damage Clinical ... • Peripheral smear ... significant fibrin clot formation ... treatment #management #hematology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Aplastic Anemia ... Clinical Presentation ... virus (EBV) • Leukemia ... • ↓ WBC • ↓ PLT ... #oncology #hematology
Low Alkaline Phosphatase - Hypophosphatasia Is Low Alkaline Phosphatase Of Clinical Importance? ALP enzyme- Discovered in 1923 Low
Phosphatase Of Clinical ... Adult form: Less ... • Pernicious anemia ... hydroxyapatite crystal formation ... Hyophosphatasia #hepatology
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