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hematology diagnosis differential oncology management workup 4factorpcc agglutinin algorithm blood causes cell chronic cll cold disease dosing gammopathy gap globulin
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework Hematologic disorder characterized by the presence of either
Hematologic disorder ... No evidence of anemia ... insufficiency, Anemia ... , or a related disorder ... #Significance #hematology
Blood Disorders - Markers and Differential Diagnosis Algorithm Acute • Myloid (AML) - CD13, CD33, CD34,
Blood Disorders ... Pelger-Huet, Macrocytic anemia ... o CML - bcr-able ... o Other bcr-able ... #hematology #Markers
Cold Agglutinin Disease 3 Types of Cold Sensitive Antibodies: 1. Cold Agglutinins (CAD) 2. Donath-Landsteiner
lymphoproliferative disorder ... • Symptoms of anemia ... • hemolytic anemia ... IgM Includes Disorders ... #hematology #diagnosis
Causes of Thrombocytopenia and Platelet Disorders - Differential Diagnosis and Workup History: - Prior platelet count, family
Thrombocytopenia and Platelet Disorders ... for decreased PLT ... for decreased PLT ... changes), high MCV anemia ... Causes #Workup #hematology
Chronic Lymphocytic Leukemia (CLL) - Summary Overview: • Most common leukemia in adults • Disorder of
leukemia in adults • Disorder ... 5) Symptoms of anemia ... marrow failure with anemia ... fludarabine) 3) Monoclonal ... Leukemia #oncology #hematology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Can Feature A Monoclonal ... Amyloidosis and monoclonal ... Organomegaly+↑RBC/plt ... (-) hemolytic anemia ... Paraproteinemias #Hematology
REBEL Review 90: Weight Based 4 Factor PCC Dosing #Hematology #Management #Table #4FactorPCC #REBELReview #Pharmacology #Dosing
Based 4 Factor PCC ... Dosing #Hematology ... #Management #Table ... #REBELReview #Pharmacology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
it represents a monoclonal ... Causes of Monoclonal ... endocrinopathy, monoclonal ... Connective tissue disorders ... Thalassemia, Sickle cell anemia
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
Biopsy: Solitary disorder ... tissue composed of monoclonal ... • No CRAB - no anemia ... UPEP, Serum IFE, FLC ... Diagnosis #Workup #Hematology
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