10 results
Multiple Myeloma and Monoclonal Gammopathies
C - HyperCalcemia- calcium > 11 mg/dL / >1 mg/dL the ULN
R
Multiple Myeloma and Monoclonal ... 40 ml/min A - Anemia ... Look for gamma gap ... if this is is monoclonal ... MGUS #diagnosis #hematology
REBEL Review 90: Weight Based 4 Factor PCC Dosing 

#Hematology #Management #Table #4FactorPCC #REBELReview #Pharmacology #Dosing
Based 4 Factor PCC ... Dosing #Hematology ... #Management #Table ... #REBELReview #Pharmacology ... #Dosing #WeightBased
Monoclonal Gammopathy of Undetermined Significance (MGUS) - Summary Framework

Hematologic disorder characterized by the presence of either
No evidence of anemia ... insufficiency, Anemia ... increased kappa FLC ... increased lambda FLC ... #Significance #hematology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4)

Work-up of an Elevated Globulin Gap:
•
it represents a monoclonal ... Causes of Monoclonal ... endocrinopathy, monoclonal ... gastric tumors • Hematology ... Thalassemia, Sickle cell anemia
Intern Pocket Cards - Inpatient Bowel Regimen Guide
Osmotic agents (draws water into bowel, thereby loosening stool
fluid overload, gas ... water enema - Discomfort ... during procedure ... #constipation #pharmacology ... #table #agents
Paraproteinemias

Entities That Can Feature A Monoclonal Protein/M Component:
• MM
• WM
• MGUS
• MGCS
• MGRS
• Splenic Marginal Zone
Can Feature A Monoclonal ... Organomegaly+↑RBC/plt ... (-) hemolytic anemia ... Pseudohyponatremia • ↓anion gap ... Paraproteinemias #Hematology
Managing warfarin INR

Warfarin dosage must be individualized according to the patient's response to the drug, and
management #algorithm #pharmacology ... #medications #table ... decisionaid #cardiology #hematology ... #warfarin #dosing
Leukemias Overview: ALL, CML, AML, APML, CLL

Acute leukemias > 20% blasts in the peripheral blood smear
mass • Rapidly rising ... activity • ↓ LAP ... - infiltrates (anemia ... count • ↓Hg & PLT ... #Leukemia #Hematology
Rybelsus (oral semaglutide) - First Oral GLP-1 Agonist
Dosing:
3 mg daily x 30 days, then 7 mg
) - First Oral GLP ... -1 Agonist Dosing ... oral route by using ... drug to remain stable ... semaglutide #Diabetes #Pharmacology
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
tissue composed of monoclonal ... • No CRAB - no anemia ... UPEP, Serum IFE, FLC ... Diagnosis #Workup #Hematology