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diagnosis hematology differential classification diffuse gap globulin hodgkins leukemia lymphadenopathy management mds monoclonal myelodysplasia myelodysplastic paraproteinemias plasmacytoma protein proteingap solitary
Causes of Diffuse Lymphadenopathy - Differential Diagnosis Algorithm Reactive: - Systemic Inflammatory •
Causes of Diffuse ... Reed-Sternberg Cells ... Lymphadenopathy #LAD ... #Causes #Hematology ... #Oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
activity • ↓ LAP ... -> AML: Blast crises ... - infiltrates (anemia ... lymphoma #Leukemia ... #Hematology #Oncology
Hodgkin's Lymphoma Overview Hodgkin's lymphoma (HL) is an uncommon hematological malignancy arising from mature B cells. It
Weight loss • Anemia ... Immune hemolytic anemia ... Workup: • Full ... classification #hematology ... #oncology #management
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... formed or don’t work ... compounds, alcohol, lead ... Workup: • Complete ... #oncology
Paraproteinemias Entities That Can Feature A Monoclonal Protein/M Component: • MM • WM • MGUS • MGCS • MGRS • Splenic Marginal Zone
Marginal Zone Lymphoma ... (HCV) • CLL & ... Marginal zone lymphoma ... (-) hemolytic anemia ... Differential #Diagnosis #Oncology
Elevated Globulin - Protein Gap (Total Protein - Albumin > 4) Work-up of an Elevated Globulin Gap: •
Albumin > 4) Work-up ... Amyloidosis • Lymphoma ... myeloma • Plasma cell ... : Lymphoma, Leukemia ... anemia • Other
Solitary Cell Plasmacytoma What? • Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma) • In 3%
• No CRAB - no anemia ... • Non-Hodgkin Lymphoma ... #Plasmacytoma #Oncology ... #Diagnosis #Workup ... #Hematology
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