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diagnosis hematology management blood leukemia myelodysplastic product reactions algorithm anemia chronic cll differential liver lymphocytic myelodysplasia syndrome syndromes transfusion transfusions
Myelodysplastic Syndrome (MD) - Diagnosis and Management Summary myelo (marrow) -dys- (abnormal) -plastic (shape) = funny-shaped cells
dys- (abnormal) -plastic ... old, ~10,000 new cases ... transformation to acute ... Myelodysplastic #Syndrome #MDS ... #hematology #oncology
Causes of Acute Liver Injury - Differential Diagnosis Hepatocellular - Liver Parenchyma • Infectious: Hepatitis C, A,
Causes of Acute ... Disease, Sickle Cell ... Pancreatic Pseudocyst, Cancer ... - Sophia Hayes MD ... #hepatology
Aplastic Anemia - Overview Who? • M = F • 3 peaks: 1) Childhood 2) 15-25 years 3) >60 years What? • Aplastic anemia
Marrow (Toxic injury ... and petechiae Causes ... • ↓ WBC • ↓ PLT ... anemia Treatment ... #Anemia #oncology
Chronic Lymphocytic Leukemia - Summary Cancer affecting lymphocytes/Mature B cell neoplasm • Lymphocytes accumulate in large numbers
Leukemia - Summary Cancer ... aplasia • ITP ... microglobulin Treatment ... ’s lymphoma or acute ... diagnosis #workup #oncology
Leukemias Overview: ALL, CML, AML, APML, CLL Acute leukemias > 20% blasts in the peripheral blood smear
Acute leukemias ... -> AML: Blast crises ... lymphoid organs When Cancer ... #Leukemia #Hematology ... #Oncology #Diagnosis
Myelodysplastic Syndromes (MDS) What? Myelodysplastic syndromes are a group of disorders caused by blood cells that are poorly
group of disorders caused ... Out Secondary Causes ... • Anemia • Aplastic ... Syndromes #diagnosis #hematology ... #oncology
Blood Transfusion Reactions Immune Mediated: • Febrile Non-Hemolytic Transfusion Reaction (FNHTR): Most common immune reaction to transfusion.
• Acute Hemolytic ... Transfusion Related Acute ... Lung Injury (TRALI ... due to marrow aplasia ... potassium from lysed cells
Blood Product Transfusions One Pager Summary Type and screen - determines blood type and detects in recipient
- Acute Hemolytic ... Lung Injury (TRALI ... due to marrow aplasia ... potassium from lysed cells ... by Nick Mark MD
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