8 results
Anticoagulants Common Reversal Agents
 - Warfarin (Coumadin) → Vitamin K (Phytonadione), 4-factor PCC (Kcentra)
 - Heparin/LMWH
Phytonadione), 4-factor PCC ... Andexxa), 4-factor PCC ... (Kcentra) #anticoagulation ... #doac #noac #pharmacology ... #hematology #reversal
Patient risk stratification algorithm for the treatment of cancer-associated thrombosis.

Currently, edoxaban and rivaroxaban are the only
algorithm for the treatment ... anticoagulants (DOACs ... Cancer #Algorithm #Anticoagulation ... #Management #Hematology ... #Oncology
(DOAC interactions) Cancer-treatment specific inducers (↑) and inhibitors (↓)
of cytochrome p450 CYP3A4 and P-glycoprotein.

DOACs are substrates
(DOAC interactions ... ) Cancer-treatment ... DOACs are substrates ... #Chemotherapy #Oncology ... #Hematology #Interactions
Treatment algorithm for VTE in Malignancy

(A) Suggested treatment algorithm for symptomatic and incidental DVT or PE
DOAC, direct oral ... #DOAC #VTE #Malignancy ... Cancer #Algorithm #Anticoagulation ... #Management #Hematology ... #Oncology
Heparin Induced Thrombocytopenia (HIT) - Diagnosis and Management - GrepMed Handbook

Presentation: 
 • Plts ↓50% (nadir
heparin-PF4 complex → plt ... hypercoagulable state and plt ... , Bivalirudin, DOAC ... Diagnosis #Management #Treatment ... #Hematology #HemeOnc
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
Triggers: ATRA treatment ... Renal Failure Treatment ... fluid overload, PCC ... diagnosis #management #hematology ... #oncology
Aplastic Anemia - Overview

Who?
• M = F
• 3 peaks:	1) Childhood	2) 15-25 years	3) >60 years

What?
• Aplastic anemia
• ↓ WBC • ↓ PLT ... aplastic anemia Treatment ... Aplastic #Anemia #oncology ... #hematology #diagnosis
Solitary Cell Plasmacytoma

What?
• Plasma cell neoplasms can present as a single lesion (solitary plasmacytoma)
• In 3%
UPEP, Serum IFE, FLC ... Bone marrow Treatment ... #Plasmacytoma #Oncology ... Diagnosis #Workup #Hematology