PLC im differential table classification em pe diagnosis gi low risk management rheumatology apml

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Differentiation Syndrome in APML
Epidemiology:
• Incidence: common in APL (2-48% depending on the study)
• Triggers:

Attempt if high risk ... initiation • Differential ... (sepsis), PE, DAH ... fluid overload, PCC ... #diagnosis #management

SLE (Systemic Lupus Erythematosus)

Suspect:
Clinical evidence of (fatigue, rash, photosensitivity, inflammatory arthritis, weight loss, and fever) and

anti-Smith Ab, low ... Skin Disease Classification ... permanent alopecia Differential ... pericardial/abd GI ... Thrombosis highest risk

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