8 results
Abnormal Liver Function Tests - Differential Diagnosis Algorithm for Transaminitis
Hepatocellular Pattern (ALT or AST > ALP):
Abnormal Liver Function ... Ducts - PBC ... , PSC, Alcoholic ... Biliary stricture, PSC ... Algorithm #diagnosis #hepatology
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
been reported (eg AIH-PBC ... upper limit of normal ... Hepatitis (eg Viral) Management ... #Diagnosis #Management ... #Hepatology
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
• Drugs • AIH ... disease US — Normal ... Bile Ducts • PSC ... Others #LFTs #Hepatology
Chest radiography showed perihilar opacities in both lungs with free air in the mediastinum (Panel A,
lungs with free air ... #Clinical #PCC # ... IM #EM #Pneumomediastinum ... #Influenza #NEJM
Trick of the Trade: Naloxone Dilution for IV Use - Given that many ED overdose patients
Draw up 9 mL of normal ... #Management #EM ... #IM #PCC #Naloxone
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
(>10^6 IU/mL), normal ... Presence of CP or PC ... family history of HCC ... #Indications #management ... #hepatology
Differentiation Syndrome in APML
Epidemiology:
 • Incidence: common in APL (2-48% depending on the study)
 • Triggers:
500 mg QD until normal ... fluid overload, PCC ... APML #diagnosis #management ... #hematology #oncology
Primary Biliary Cirrhosis - Management
A. Initiate therapy 
 - Initiate 1st line therapy with UDCA (13-15
Biliary Cirrhosis - Management ... 1.5x ULN and/or abnormal ... Non-pharmacological management ... survey disease #PBC ... #Treatment #hepatology