15 results
Causes of Acute Liver Injury - Differential Diagnosis
Hepatocellular - Liver Parenchyma
 • Infectious: Hepatitis C, A,
Causes of Acute ... Malignancy, 1° PBC ... , 1° PSC, Cystic ... #Acute #algorithm ... #hepatology
Alkaline Phosphatase (ALP) Elevation - Differential Diagnosis Algorithm

ALP:
 - Enzymes that catalyze hydrolysis of organic phosphate
Differential Diagnosis Algorithm ... Intestine - Other causes ... biliary Cholangitis (PBC ... - PSC - Other ... #hepatology
Acute Liver Injury - Differential Diagnosis Algorithm

Vascular Causes of Acute Liver Injury: 
 • Hepatic vein:
Vascular Causes ... Autoimmune hepatitis, PBC ... , PSC, IgG4, HLH ... stone, Malignancy, PBC ... , PSC, Cystic fibrosis
Elevated Liver Enzymes - Differential Diagnosis Algorithm
Severe ALT > 15x ULN
 • Viral
 • Drugs/Toxins
 •
Differential Diagnosis Algorithm ... • Cholestatic disease ... Bile Ducts • PSC ... Others #LFTs #Hepatology ... #Causes
Autoimmune Hepatitis

Clinical Presentation
 - Highly variable clinical presentation, from subclinical disease to acute liver failure.
 -
from subclinical disease ... pattern of liver injury ... reported (eg AIH-PBC ... regarding need for treatment ... #Hepatology
Drug Induced Liver Injury (DILI) - Stepwise Diagnosis Algorithm
DILI suspicion
Features toxic aetiology: Skin involvement, Kidney injury,
Stepwise Diagnosis Algorithm ... non-essential drug/HDS treatments ... for alternative causes ... Alcohol-related liver disease ... #hepatology
Hepatitis B - Treatment Indications
Treatment not indicated:
 • Immune tolerant state - HBe-Ag detectable, high HBV
Presence of CP or PC ... family history of HCC ... with severe liver injury ... #Indications #management ... #hepatology
Chagas Disease - American Trypanosomiasis - Diagnosis and Management Summary
Chagas disease (American trypanosomiasis) is an infectious
Diagnosis and Management ... caused by the protozoan ... others: AV blocks, PVC ... Trypanosomiasis #Diagnosis #Management ... #Treatment
Borrelia recurrentis on Peripheral Blood Smear
23M Somali refugee recently arrived w/severe abd pain, confusion and fever
12.5, WBC 14, Plt ... Specific organ injury ... or PenG 800K U IM ... initiation of treatment ... Infectious Diseases
Disseminated Intravascular Coagulation (DIC) Overview

Increased Clotting and Consumption of Clotting Factors

Findings:
 • Bleeding
 • Recent history
• Severe Liver Disease ... + Bleeding Treatment ... Treat primary cause ... #treatment #management ... #hematology